The debate will be carried on television and online by WISH (Indianapolis), WTVW (Evansville), WANE (Fort Wayne) and WTWO (Terre Haute) at 7p.m.
The trio are lining up to face Sen. Joe Donnelly, the incumbent Democrat.
WISH-TV news anchor Brooke Martin will be the moderator and one of three panelists. The other panelists will be Brad Byrd, the main news anchor at WEHT-TV in Evansville, and David Williams, the WISH-TV/Nexstar Indiana Statehouse bureau chief.
WISH-TV Daybreak anchor Scott Sander will host specials before and after the debate on WISHTV.com.
You can submit questions to be considered for the debate on this Facebook post or by using the form below.